The kidney among the husband and wife transplant

1 type is a different gene marrow to transplant.(1970's clinical application, have already obtained very great success)It needs to be have mutually match together a full brothers, sister with the white cell antigen(HLA) of sufferer mankind and very few number of have no relative relate to of provide Sui input of different body marrow, or family member such as the marrow of the parents and sons and daughters transplant;And have nothing to do with sufferer HLA not and very matching of marrow of provide.The brothers sister of non- compatriot although the HLA mutually matches, the easy occurrence importance doesn't wait of the transplantation thing anti- host disease(GVHD), particularly at after a kind of circumstance is more serious.Transplanting with gene marrow is another , namely very few count of together egg double foetus twin brothers or the marrow of the sister transplantation.
Still having 1 type is stillfrom the body marrow to transplant(ABMT).This kind of marrow transplantation opens an exhibition to compare with night, , 80's applied in clinical.Use the marrow of oneself, not the one who need to provide Sui, this method is simple, be easy to expansion, can used for only sons and daughters, and have no GVHD occurrence.Used for leukemia, lymphoid lump and various treatments of entity lumps.
Mankind white cell antigen(HLA) gene the point is exist in the short arm of two No.6th chromosomes in the meantime up, each top constitutes to°from the complicated gene point of close catena again.Each orders all 1 within gene to constitute from several or several ten etc..On the cell membrane, the antigen discover has already have currently 200 kinds of or so.Only have HLA － A － B-C the HLA antigen that can examine currently in the laboratory, -D/DR this several big type.Laboratory measure two people's this a few antigens agree with to match and be unequal to have no not to agree with in two people's all antigens of place.In together the full brothers, sister paternal uncle the mother is each accept a chromosome top grows gene each time of 1, so is a monoploid gene heredity.Together full brothers sister's gene match's method completely the homology rate only has 25%, parents and son generation, always has the AN of a single chromosome top HLA, B etc. point of match dissimilarity, past in addition to together twin brothers or sister of egg outside, family member and irrelevant provide the HLA mutually matches of the probability be very few.
The HLA is at the beginning the main organization compatibility of the mankind compound(MHC) and disheveled hair now, the antigen that its gene express when code, the participation control immunity identify and cell second cluster interaction, past the HLA not and mutually matches to transplant thing with be subjected to the mutually reject of of the organization influence.Clinical up on the other hand can produce transplantation thing can't plant to live, can produce importance not to wait on the other hand of impatient and chronic transplant the thing anti- host disease, the performance is skin, liver and stomach and intestines way pathological changes and the serious can cause to die.Therefore, whether HLA organization goes together with the success that the type transplants to choice and marrow which provides a Sui or not, is one of the important links.
BE about 60% adults impatient leukemia sufferer, through different gene or together the gene marrow transplantation can reach to above grow an existence period for 3 years and the part already is above for 5~6 years.At chronic grain period with chronic cell leukemia, being about 80% patients can survive above for 3 years, the part has already survive 5~6 years above, it may be said cure for good.Someone compared to use the chemistry treatment of the normal regulations consociation, don't do the impatient leukemia of marrow transplantation and only have 10 ～ 15% people survive till 3 years, the average existence expects to be only around a year.Chronic grain the existence period of the cell leukemia average 3~4 years, course of illness although slowness, use currently the chemotherapy method cured for good of possibility.Therefore, the curative effect that marrow obtain when transplant to compare with normal regulations chemotherapy, for good.To lymphoid lump and other entity lump the application is from the body marrow transplant may also attain to cure for good of purpose.

The marrow transplantation success rate is subjected to many factors in time a test:
Only one by one in order and smoothly pass above these five passes, and make a gene check after half year, discover the gene expression which provides a Sui in the sufferer's body, and marrow, blood elephant and important and dirty machine check normal, have no obvious symptom, just calculate real success.
Clinical ascend some familiar sufferers are after transplant a cabin January, even appear to relapse after a year in Marchary and in June.This respond, transplants the complications of process with sufferer's condition type, the machine body dirty machine function, oneself immunity and is provided for Sui and the sufferer's gene point to match to agree with a rate and transplants the comprehensive level of hospital and has an equal relation.
The marrow transplants currently real transplant success rate news medium to report about 50%, but the medical science field approve about 33%.Namely 1/3 and 1/3 and 1/3 standpoints:1/3 sufferers fail in the transplantation;1/3 relapse in the transplantation the empress half year;1/3 sufferers be transplanted success.
The marrow transplants expenses:
Because sufferer's condition, complications, blood transfusion quantity, the medicine use, enter cabin time length etc. relevant, generally about 15-500,000 dollars.
Go together with a type once in 4000 dollars/time, general get at 3-4 or so.
Mobilize medicine for injection, 600-800 dollars not only provide beat, be subjected to after the cell return lose also want a dozen, beat blood elephant to rise.
Separate once 2500, freeze 5000, also need to use white egg white to develop about 2500, load separately several bags, import a bag 1300 many of, use 7 and 8.
The chemotherapy medicine have of expensive have of cheapness, the expensive 60 mls wants 24800 dollars, several dollars of cheapness.
The center vein tube have 700-1000 dollar.
The layer flows cabin for a day 1400, live for 35+ days this will 50000 many.
The blood isn't everybody to want to lose.
The preventive infection medicine not much also infects for 1000-2000 dollars of will use a good medicine, that uses to want around ten thousand.
The most is a row difference, because of ising not an own thing.The person whom some persons lightly have is heavy, uncertain, and the cabin still needs to use behind and have of row the different heavy person at most wants to spend several 100,000.
So smooth words at ten several ten thousand, serious words 20-500,000, this be the price of Peking and other places slightly have already float.

The blood composition in the human body is placed in a kind of continuous metabolism in, old cell drive clearance, born new of cell, marrow of the important function be the stem cell which produces born various cell, these stem cell pass to divide a rebirth various blood cell be like red cell, white cell, blood platelets, lymphoid cell etc. and in brief say that the medullary function is to build blood function.Therefore, life and immunity dint of maintenance machine body for marrow are count for much.

what is a marrow
The marrow is the loose quality bone of the marrow chamber and flat even bone(like Ka bone, rib, breastbone, vertebrate bone...etc.) which exists in the long bone(such as Gong bone, bone) be a kind of spongy organization within mesh of net, can produce the marrow of blood cell slightly presents red, be called red marrow.The adult's some marrows in the marrow chambers imply a lot of fat cells, assume a yellow, and can't produce blood cell and be called yellow marrow.Was full of red marrow inside whole body marrow chamber when person be born, along with the age growth, the fat cell increased in the marrow and very part of red marrows were replace by the yellow marrow, there is red marrow in at last almost only flat even bone loose quality bone.This kind variety may be because the adult doesn't need all marrow chambers to build blood, parts of marrow chambers build the blood has already enough added the blood cell needed.Crash when the body seriously lack blood, part of yellow marrows can change into red marrow and resume ability of build the blood.

The kidney transplant operation of urine poisoning disease sufferer what opportune moment should be more suitable at?This circumstance which wants very according to the sufferer and the surgical operation to decide.
Normal regulations blood deeply sufferer, transplant have to be well dialysis in previous 24 hours once, with the metabolism outcome in the clearance body, however the Shu bleeds occurrence behind.
The peritoneum dialysis sufferer generally keeps on stomach deeply until surgical operation before, if have no infection can after the kidney transplant success February again pull out a tube.But do the stomach of the Yi kidney consociation transplantation deeply a sufferer should pull out a tube while plant kidney, in order to prevent influence surgical operation operation.
Some parlances think dialysis time in half year above, after be subjected to transplant the immunity antibody in the body decrease, but plain from the wreath Bao of extensively applied, have already had no necessity to therefore request dialysis time.But parts of scholar persistence to the urine poisoning disease which suffers from easily relapsing a kidney disease sufferer, the beard keep on dialysis more than 6 months consider kidney transplantation again.
As for adopt a blood dialysis still a peritoneum be dialysis, to the sufferer kidney transplant behind the influence of kidney livability have no difference.